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publications

read the publications related to our product pipeline

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  • publication
    WCK 5107 & WCK 5153: bicyclo-acyl hydrazides PBP2 inhibitors showing potent beta-lactam enhancer activity against Acinetobacter baumannii, including multidrug-resistant (MDR) carbapenemase-producing clinical strains
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    Electrocardiographic effects of WCK 2349
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    Plasma and intrapulmonary pharmacokinetics of levonadifloxacin in healthy adults
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    Single-center, phase 1, open label, single dose study to evaluate the pharmacokinetics and safety of WCK 2349 in patients with hepatic impairment
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    Safety and pharmacokinetics of multiple ascending doses of WCK 771 and WCK 2349
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    Pharmacodynamics of cefepime and tazobactam against carbapenemase positive strains in a neutropenic mouse model
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    WCK 4282 (cefepime-tazobactam) MIC quality control ranges using a multi-laboratory study design
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    WCK 4282 (high-dose cefepime-tazobactam) against multi-resistant Gram-negative bacteria
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    Antimicrobial activity of WCK 4282 (high-dose cefepime-tazobactam) tested against Gram-negative organisms from medical centres located in Europe and the Asia-Pacific region
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    In vitro activity of WCK 4282 (high-dose cefepime-tazobactam) against resistant subsets of Enterobacteriaceae collected worldwide (2014)
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    WCK4282 (high-dose cefepime-tazobactam) antimicrobial activity against Gram-negative organisms from United States (USA) and Latin American medical centres (2014)
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    Safety, tolerability and pharmacokinetics of WCK 4282 (fep-taz) in healthy adult subjects
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    WCK 4282 (high-dose cefepime-tazobactam) extends coverage to carbapenem-resistant Klebsiella harbouring multiple ESBLs, OXA 48/181 in conjunction with impermeability
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